Long-Term Outcomes of Prostate-Specific Membrane Antigen-PET Imaging of Recurrent Prostate Cancer.

ABSTRACT:

Importance

Although prostate-specific membrane antigen positron emission tomography (PSMA-PET) has shown improved sensitivity and specificity compared with conventional imaging for the detection of biochemical recurrent (BCR) prostate cancer, the long-term outcomes of a widespread shift in imaging are unknown.

Objective

To estimate long-term outcomes of integrating PSMA-PET into the staging pathway for recurrent prostate cancer.

Design, setting, and participants

This decision analytic modeling study simulated outcomes for patients with BCR following initial definitive local therapy. Inputs used were from the literature and a retrospective cohort study conducted at 2 institutions. The base case analysis assumed modest benefits of earlier detection and treatment, and sc

SUBMITTER: Kunst N 

PROVIDER: S-EPMC11581571 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature