Lipodermatosclerosis and Pulmonary Hypertension in Systemic Sclerosis.

ABSTRACT:

Importance

Lipodermatosclerosis (LDS) stems from vascular dysfunction and dermal inflammation and thereby is mechanistically similar to systemic sclerosis (SSc). The association of LDS with SSc in the clinical setting has not been well characterized in the literature.

Objective

To evaluate the prevalence of LDS in SSc and the association of LDS with vascular complications, particularly pulmonary hypertension, in patients with SSc.

Design, setting, and participants

This retrospective cohort study used prospectively collected longitudinal data from a cohort of patients from the multidisciplinary rheumatology and dermatology clinic at a single tertiary care center from November 2004 to November 2022. Adult patients (aged ≥18 years at the time of cohort entry) with SSc we

SUBMITTER: Davuluri S 

PROVIDER: S-EPMC11581578 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature