Titration Protocol for Upper Airway Stimulation in Pediatric Patients With Down Syndrome.

ABSTRACT:

Importance

Upper airway stimulation (UAS) was recently approved to treat persistent obstructive sleep apnea in pediatric patients with Down syndrome. Appropriate titration of the UAS implantable device is essential to achieve optimal outcomes, but standardized titration protocols for young patients are lacking.

Objective

To develop and share a UAS titration protocol for pediatric patients with Down syndrome.

Design, setting, and participants

This small cohort study of pediatric patients with Down syndrome presents a standardized UAS stimulation titration protocol for conducting postimplantation polysomnograms. The protocol was developed through a multidisciplinary collaboration at a tertiary children's hospital with a dedicated pediatric polysomnogram laboratory. The

SUBMITTER: Frederick RM 

PROVIDER: S-EPMC11581599 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature