Survival and Treatment Patterns in Stage II to III Esophageal Cancer.

ABSTRACT:

Importance

Existing clinical trials favor neoadjuvant chemoradiation therapy (NCRT) followed by surgery alone for locally advanced esophageal cancer (EC) and perioperative chemotherapy as the preferred modality for esophageal adenocarcinoma (EAC). However, it is unclear whether these trial findings are reflected in the patterns of care and survival outcomes among patients in the clinical setting.

Objective

To investigate survival outcomes in the clinical setting among patients with EC after various treatment modalities.

Design, setting, and participants

This retrospective cohort study examined data from the National Cancer Database maintained by the American College of Surgeons and focused on patients with clinical stage II or III EC, excluding those with gastroesopha

SUBMITTER: Jeon WJ 

PROVIDER: S-EPMC11581628 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature