Variation in Opioid Agonist Dosing in Clinical Trials by Race and Ethnicity.

ABSTRACT:

Importance

Racial and ethnic disparities in access to treatment and quality of treatment for opioid use disorder (OUD) have been identified in usual care settings. In contrast, disparities in treatment quality within clinical trials are relatively unexamined.

Objective

To estimate racial and ethnic differences in the dose of opioid agonist treatment for OUD in the first 4 weeks of treatment in clinical trials.

Design, setting, and participants

This cohort study performed analysis of the methadone and buprenorphine treatment arms of 3 trials conducted by the National Institute on Drug Abuse Clinical Trials Network between May 2006, and January 31, 2017, at multiple Clinical Trials Network sites across the US. Trial participants who were randomized to and initiated bupr

SUBMITTER: Ross RK 

PROVIDER: S-EPMC11581645 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature