Postprostatectomy Radiotherapy Timing and Long-Term Health-Related Quality of Life.

ABSTRACT:

Importance

The association between radiotherapy (RT) timing after radical prostatectomy and long-term patient-reported health-related quality of life (HRQOL) in men with prostate cancer is unknown.

Objective

To measure long-term HRQOL in men with prostate cancer up to 15 years after prostatectomy with or without RT and examine whether early vs late postprostatectomy RT is associated with differences in sexual, urinary, and bowel HRQOL.

Design, setting, and participants

A prospective, multicenter, longitudinal cohort analysis using HRQOL data from the PROST-QA (2003-2006) and RP2 consortium (2010-2013) studies was conducted. Men with localized prostate cancer undergoing radical prostatectomy were included. Data were analyzed between May 8, 2023, and March 1, 2024. The

SUBMITTER: Patel SA 

PROVIDER: S-EPMC11581678 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature