Trends in Mortality in People With HIV From 1999 through 2020: A Multicohort Collaboration.

ABSTRACT:

Background

Mortality among people with human immunodeficiency virus (HIV) declined with the introduction of combination antiretroviral therapy. We investigated trends in mortality in people with HIV from 1999 through 2020.

Methods

Data were collected from the Data Collection on Adverse events of Anti-HIV Drugs (D:A:D) cohort between January 1999 through January 2015 and the International Cohort Consortium of Infectious Disease (RESPOND) from October 2017 through December 2020. Age-standardized all-cause and cause-specific mortality rates, classified using Coding Causes of Death in HIV, were calculated. Poisson models were used to assess mortality over time.

Results

Among 55 716 participants followed for median 6 years (interquartile range, 3-11), 5263 died (mortality

SUBMITTER: Tusch E 

PROVIDER: S-EPMC11581700 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature