Detection, Patterns, and Outcomes of Recurrent HPV-Positive Oropharyngeal Squamous Cell Carcinoma.

ABSTRACT:

Importance

Recurrent human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) is a relatively rare but serious disease with little empirical data. Previous works have studied patterns of recurrence in HPV-positive OPSCC, but only one has studied truly recurrent disease as opposed to persistent disease, and no work systematically analyzed posttreatment surveillance imaging strategies and how recurrences were detected.

Objective

To refine the understanding of HPV-positive OPSCC recurrence and inform optimal imaging surveillance strategies.

Design, setting, and participants

This retrospective cohort study involved electronic medical record review at a tertiary care hospital. Patients treated for OPSCC from 2012 to 2019 were extracted, and patient

SUBMITTER: Shah R 

PROVIDER: S-EPMC11581730 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature