Weight and Lipid Levels in People Living With HIV and Initiating a Dolutegravir-Based Regimen in a Resource Limited Setting: A Prospective Study.

ABSTRACT: Background: Following the 2018 World Health Organization's (WHO) guidelines on HIV treatment and management, the Zimbabwean government has embraced dolutegravir (DTG)-based regimens as the preferred first-line treatment for people living with HIV (PLWH). Despite this implementation, there remains a paucity of knowledge on the potential associations between DTG-based regimens, body weight and blood lipid levels among PLWH in Zimbabwe. Thus, the aim of this study was to investigate variances in body weight and blood lipid levels at two distinct timepoints-baseline and 6-month post-DTG initiation. Methods: We conducted this study between November 2021 and April 2023 among ART-naïve individuals initiating a DTG-based regimen. Participants were recruited from a tertiary clinic in

SUBMITTER: Chakanetsa R 

PROVIDER: S-EPMC11581792 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature