Comparative bioavailability study of supplemental oral Sucrosomial ^® vs. oral conventional vitamin B12 in enhancing circulatory B12 levels in healthy deficient adults: a multicentre, double-blind randomized clinical trial.

ABSTRACT:

Background

Vitamin B12 is essential for neurological function, red blood cell formation, and DNA synthesis. Deficiency can lead to diverse health conditions, including megaloblastic anemia and neurological issues. Oral supplementation is a standard treatment for B12 deficiency. The Sucrosomial^® carrier system offers an innovative approach that enhances supplemental nutrient absorption and bioavailability.

Objectives

This study aimed to compare the effectiveness of oral Sucrosomial^® vitamin B12 formulation vs various conventional B12 supplements, randomly selected from local pharmacies, in increasing and maintaining circulatory B12 levels in healthy deficient adults (200-300 pg/mL).

Methods

A randomized, double-blind clinical trial was conducted a

SUBMITTER: Memon NM 

PROVIDER: S-EPMC11581850 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature