Improving the lesion appearance on FLAIR images synthetized from quantitative MRI: a fast, hybrid approach.

ABSTRACT:

Objective

The image quality of synthetized FLAIR (fluid attenuated inversion recovery) images is generally inferior to its conventional counterpart, especially regarding the lesion contrast mismatch. This work aimed to improve the lesion appearance through a hybrid methodology.

Materials and methods

We combined a full brain 5-min MR-STAT acquisition followed by FLAIR synthetization step with an ultra-under sampled conventional FLAIR sequence and performed the retrospective and prospective analysis of the proposed method on the patient datasets and a healthy volunteer.

Results

All performance metrics of the proposed hybrid FLAIR images on patient datasets were significantly higher than those of the physics-based FLAIR images (p < 0.005), and comparable to those of conv

SUBMITTER: Xu F 

PROVIDER: S-EPMC11582199 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature