Temporal trends in the prevalence of major birth defects in China: a nationwide population-based study from 2007 to 2021.

ABSTRACT:

Background

Birth defects constitute a significant public health issue worldwide, yet there is a lack of comprehensive population-based data for the Chinese population.

Methods

We analyzed data from the China National Population-based Birth Defects Surveillance System from 2007 to 2021, we calculated the prevalence rates of selected birth defects, stratified by maternal residence, geographic region, maternal age, and infant sex. The Joinpoint regression model was utilized to assess trends and annual percent changes in prevalence.

Results

From 2007 to 2021, significant downward trends in prevalence were observed for neural tube defects (NTDs), hydrocephalus, cleft lip with or without palate (CL/P), limb reduction defects (LRD), omphalocele, Down syndrome, and tetralogy

SUBMITTER: Li WY 

PROVIDER: S-EPMC11582329 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature