A retrospective two-center cohort study of the bidirectional relationship between depression and tinnitus-related distress.

ABSTRACT:

Background

Tinnitus can cause considerable psychological distress among patients, particularly if comorbidities occur. Despite a strong relationship between tinnitus-related distress and depression, the underlying mechanisms represent a long-standing question. By investigating the co-development of tinnitus-related distress and depressiveness throughout therapy, we capture the dynamic interplay of both conditions and uncover underlying common features mediating their link.

Methods

Large datasets from two different day clinics in Germany have been analyzed using a regularization method for predictor selection (analysis 1) and latent growth curve modeling (LCM; analysis 2). Tinnitus-related distress was assessed using the Tinnitus Questionnaire (TQ). All patients have been exp

SUBMITTER: Lukas CF 

PROVIDER: S-EPMC11582723 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature