Estimated Effectiveness of Influenza Vaccines in Preventing Secondary Infections in Households.

ABSTRACT:

Importance

Influenza vaccine effectiveness (VE) is commonly assessed against prevention of illness that requires medical attention. Few studies have evaluated VE against secondary influenza infections.

Objective

To determine the estimated effectiveness of influenza vaccines in preventing secondary infections after influenza was introduced into households.

Design, settings, and participants

During 3 consecutive influenza seasons (2017-2020), primary cases (the first household members with laboratory-confirmed influenza) and their household contacts in Tennessee and Wisconsin were enrolled into a prospective case-ascertained household transmission cohort study. Participants collected daily symptom diaries and nasal swabs for up to 7 days. Data were analyzed from Septemb

SUBMITTER: Grijalva CG 

PROVIDER: S-EPMC11582933 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature