Oncologic outcomes of screen-detected and non-screen-detected T1 colorectal cancers.

ABSTRACT:

Background

The incidence of T1 colorectal cancer (CRC) has increased with the implementation of CRC screening programs. It is unknown whether the outcomes and risk models for T1 CRC based on non-screen-detected patients can be extrapolated to screen-detected T1 CRC. This study aimed to compare the stage distribution and oncologic outcomes of T1 CRC patients within and outside the screening program.

Methods

Data from T1 CRC patients diagnosed between 2014 and 2017 were collected from 12 hospitals in the Netherlands. The presence of lymph node metastasis (LNM) at diagnosis was compared between screen-detected and non-screen-detected patients using multivariable logistic regression. Cox proportional hazard regression was used to analyze differences in the time to recurrence (TT

SUBMITTER: van der Schee L 

PROVIDER: S-EPMC11583000 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature