Prevalence and predictive factors of colorectal sessile serrated lesions in younger individuals.

ABSTRACT:

Background

Sessile serrated lesions (SSLs) are obscured lesions predominantly in the right-sided colon and associated with interval colorectal cancer; however, their prevalence and risk factors among younger individuals remain unclear.

Methods

This retrospective study enrolled individuals who underwent index colonoscopy. The primary outcome was the SSL prevalence in the younger (<50 years) and older (≥50 years) age groups, while the secondary outcomes included clinically significant serrated polyps (CSSPs). Multivariable logistic regression was employed to identify predictors.

Results

Of the 9854 eligible individuals, 4712 (47.8%) were categorized into the younger age group. Individuals in the younger age group exhibited lower prevalences of adenomas (22.6% vs. 46.2%;

SUBMITTER: Yeh JH 

PROVIDER: S-EPMC11583004 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature