A assessment of the effects of parental age on the development of autism in children: a systematic review and a meta-analysis.

ABSTRACT:

Objective

There has been conflicting evidence in earlier research on the association between parental age and autism risk. To clarify this association, we conducted a comprehensive meta-analysis of observational studies. The primary objective of this study was to determine the association between parents' age and the risk of autism in the offspring.

Methods

PubMed, EMBASE and Web of Science were searched for reports published up to November 2023. Results from relevant studies were pooled using random effects models. Subgroup analyses and meta-regression were performed to examine heterogeneity between the studies. Studies were included in this meta-analysis that focused on children with autism and examined the relationship between parents' age (mother or father) and the risk

SUBMITTER: Dehesh T 

PROVIDER: S-EPMC11583425 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature