Establishment of an MRI-based radiomics model for distinguishing between intramedullary spinal cord tumor and tumefactive demyelinating lesion.

ABSTRACT:

Objective

Differentiating intramedullary spinal cord tumor (IMSCT) from spinal cord tumefactive demyelinating lesion (scTDL) remains challenging with standard diagnostic approaches. This study aims to develop and evaluate the effectiveness of a magnetic resonance imaging (MRI)-based radiomics model for distinguishing scTDL from IMSCT before treatment initiation.

Methods

A total of 75 patients were analyzed in this retrospective study, comprising 55 with IMSCT and 20 with scTDL. Radiomics features were extracted from T1- and T2-weighted imaging (T1&T2WI) scans upon admission. Ten classification algorithms were employed: logistic regression (LR); naive bayes (NaiveBayes); support vector machine (SVM); k nearest neighbors (KNN); random forest (RF); extra trees (ExtraTrees); eXt

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC11583559 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature