Household Transmission Dynamics of Seasonal Human Coronaviruses.

ABSTRACT:

Background

Household transmission studies inform how viruses spread among close contacts, but few characterize household transmission of endemic coronaviruses.

Methods

We used data collected from 223 households with school-age children participating in weekly disease surveillance over 2 respiratory virus seasons (December 2015 to May 2017), to describe clinical characteristics of endemic human coronaviruses (HCoV-229E, HcoV-HKU1, HcoV-NL63, HcoV-OC43) infections, and community and household transmission probabilities using a chain-binomial model correcting for missing data from untested households.

Results

Among 947 participants in 223 households, we observed 121 infections during the study, most commonly subtype HCoV-OC43. Higher proportions of infected children (<19

SUBMITTER: Quandelacy TM 

PROVIDER: S-EPMC11584005 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature