Outcomes of dermal substitutes in burns and burn scar reconstruction: A systematic review and meta-analysis.

ABSTRACT: Dermal substitutes have been introduced in burn care to improve wound healing outcomes; however, their use remains limited in standard treatments. This systematic review and meta-analysis aimed to evaluate the outcomes of dermal substitutes in patients with burns and patients requiring burn scar reconstruction and subsequently contribute to optimising the integration of dermal substitutes into clinical practice and reducing the knowledge gap. A comprehensive search across various databases included human studies from peer-reviewed journals on dermal substitutes for deep dermal and full-thickness burns, and scar reconstruction across all ages. Data from comparative trials were extracted, focusing on patient and wound characteristics, treatment specifics, and outcomes related to wound healin

SUBMITTER: van den Bosch AS 

PROVIDER: S-EPMC11584356 | biostudies-literature | 2024 Nov-Dec

REPOSITORIES: biostudies-literature