Pre-emptive use of glucose 5% as the standard drug solvent reduces hypernatremia in critically ill patients.

ABSTRACT:

Background

Hypernatremia presents a common complication in intensive care unit (ICU) patients, associated with increased mortality and length of stay. This study investigates the effect of sodium chloride 0.9% compared with glucose 5% solution as the standard intravenous drug diluent on the prevalence of hypernatremia in a medical ICU.

Methods

This is a retrospective before-and-after study comparing two consecutive patient groups before and after the standard drug solvent was changed from sodium chloride 0.9% to glucose 5% solution for compatible medications. A total of 265 adult COVID-19 patients admitted between October 2020 and March 2021 to the study ICU were included, with 161 patients in the timeframe when sodium chloride 0.9% was employed as the standard drug solvent

SUBMITTER: Hardenberg JB 

PROVIDER: S-EPMC11584513 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature