Identifying and Estimating Frailty Phenotypes by Vocal Biomarkers: Cross-Sectional Study.

ABSTRACT:

Background

Researchers have developed a variety of indices to assess frailty. Recent research indicates that the human voice reflects frailty status. Frailty phenotypes are seldom discussed in the literature on the aging voice.

Objective

This study aims to examine potential phenotypes of frail older adults and determine their correlation with vocal biomarkers.

Methods

Participants aged ≥60 years who visited the geriatric outpatient clinic of a teaching hospital in central Taiwan between 2020 and 2021 were recruited. We identified 4 frailty phenotypes: energy-based frailty, sarcopenia-based frailty, hybrid-based frailty-energy, and hybrid-based frailty-sarcopenia. Participants were asked to pronounce a sustained vowel "/a/" for approximately 1 second. The speech signal

SUBMITTER: Lin YC 

PROVIDER: S-EPMC11584546 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature