Relationship between genotype, phenotype, and refractive status in patients of inherited retinal degeneration.

ABSTRACT:

Background

To elucidate the relationship between inherited retinal disease, visual acuity and refractive error development in Asian patients.

Subjects

Five hundred phakic eyes with refractive data were analysed in this retrospective cohort. Diseases were categorized by clinical phenotypes, and the prevalent genotypes identified in the Taiwan Inherited Retinal Degeneration Project were analysed. Consecutive surveys in Taiwan have provided the rates of myopia in the general population.

Results

No differences were observed among the disease phenotypes with respect to myopia (P = 0.098) and high myopia rates (P = 0.037). The comparison of refractive error between retinitis pigmentosa and diseases mainly affecting the central retina showed no difference, and the refraction

SUBMITTER: Tsai WC 

PROVIDER: S-EPMC11584704 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature