The 1000 Chinese Indigenous Pig Genomes Project provides insights into the genomic architecture of pigs.

ABSTRACT: Pigs play a central role in human livelihoods in China, but a lack of systematic large-scale whole-genome sequencing of Chinese domestic pigs has hindered genetic studies. Here, we present the 1000 Chinese Indigenous Pig Genomes Project sequencing dataset, comprising 1011 indigenous individuals from 50 pig populations covering approximately two-thirds of China's administrative divisions. Based on the deep sequencing (~25.95×) of these pigs, we identify 63.62 million genomic variants, and provide a population-specific reference panel to improve the imputation performance of Chinese domestic pig populations. Using a combination of methods, we detect an ancient admixture event related to a human immigration climax in the 13^th century, which may have contributed to the formation of

SUBMITTER: Du H 

PROVIDER: S-EPMC11584710 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature