Computer-aided detection of retinopathy of prematurity severity assessment via vessel tortuosity measurement in preterm infants' fundus images.

ABSTRACT:

Objective

To develop a computer-aided diagnostic system for retinopathy of prematurity (ROP) disease using retinal vessel morphological features.

Methods

A total of 200 fundus images from 136 preterm infants with stage 1 to 3 ROP were analysed. Two methods were developed to measure vessel tortuosity: the peak-and-valley method and the polynomial curve fitting method. Correlations between temporal artery tortuosity (TAT) and temporal vein tortuosity (TVT) with ROP severity were investigated, and vessel tortuosity relationships with vessel angles (TAA and TVA) and vessel widths (TAW and TVW). A separate dataset from Japan containing 126 images from 97 preterm patients was used for verification.

Results

Both methods identified similar tortuosity in images without ROP and

SUBMITTER: Huang YP 

PROVIDER: S-EPMC11584778 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature