High flow nasal cannula and low level continuous positive airway pressure have different physiological effects during de novo acute hypoxemic respiratory failure.

ABSTRACT:

Background

Large tidal volumes during de novo acute hypoxemic respiratory failure (AHRF) may promote patient self-inflicted lung injury. Tidal volume assessment under high flow nasal cannula (HFNC) is not routinely feasible at the bedside. Our objective was to determine whether tidal volume during low-level continuous positive airway pressure (CPAP) could predict tidal volume during HFNC and to compare the physiological effects of HFNC and low-level CPAP.

Methods

Prospective, single-center study including 29 de novo AHRF patients treated with HFNC (50 to 60 L.min^- 1). Patients were monitored using electrical impedance tomography during HFNC then CPAP at 4 cmH₂O. Tidal volume during HFNC was calculated based on tidal impedance variation. The ability of t

SUBMITTER: Tuffet S 

PROVIDER: S-EPMC11584821 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature