Data-Driven Cutoff Selection for the Patient Health Questionnaire-9 Depression Screening Tool.

ABSTRACT:

Importance

Test accuracy studies often use small datasets to simultaneously select an optimal cutoff score that maximizes test accuracy and generate accuracy estimates.

Objective

To evaluate the degree to which using data-driven methods to simultaneously select an optimal Patient Health Questionnaire-9 (PHQ-9) cutoff score and estimate accuracy yields (1) optimal cutoff scores that differ from the population-level optimal cutoff score and (2) biased accuracy estimates.

Design, setting, and participants

This study used cross-sectional data from an existing individual participant data meta-analysis (IPDMA) database on PHQ-9 screening accuracy to represent a hypothetical population. Studies in the IPDMA database compared participant PHQ-9 scores with a major depression c

SUBMITTER: Levis B 

PROVIDER: S-EPMC11584932 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature