Cardiovascular and Kidney Outcomes of Non-Diabetic CKD by Albuminuria Severity: Findings From the CRIC Study.

ABSTRACT:

Rationale & objective

The clinical trajectory of normoalbuminuric chronic kidney disease (CKD), particularly in the absence of diabetes, has not yet been well-studied. This study evaluated the association of kidney and cardiovascular outcomes with levels of albuminuria in a cohort of patients with nondiabetic CKD.

Study design

Prospective cohort study.

Setting & participants

1,463 adults with nondiabetic CKD without known glomerulonephritis and diagnosed with hypertensive nephrosclerosis or unknown cause of CKD participating in the Chronic Renal Insufficiency Cohort (CRIC) Study.

Exposure

Albuminuria stage at study entry.

Outcome

Primary outcome: Composite kidney (halving of estimated glomerular filtration rate [eGFR], kidney transplantation, or dialysis

SUBMITTER: Shulman R 

PROVIDER: S-EPMC11585431 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature