Social determinants of participation in genetic research among Puerto Ricans and in the Puerto Rican diaspora.

ABSTRACT: Puerto Ricans are underrepresented in genetic research. This underrepresentation denies Puerto Ricans the benefit from therapeutic developments that could mitigate health disparities arising from conditions for which genetically-derived treatments exist. The Puerto Rican diaspora, especially post-2017 due to economic and environmental crises, has expanded within the USA. Prior research suggests that Latin American diaspora communities are less likely to participate in genetic research. We hypothesized, specifically, that the Puerto Rican diaspora in the USA would be less likely to participate in genetic research than would Puerto Ricans in their homeland's archipelago, and that accounting for social and cultural determinants related to the diaspora experience would mitigate this disparity.

SUBMITTER: Dye TV 

PROVIDER: S-EPMC11585439 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature