Exploring the role of irisin as a potential biomarker in adolescents and young adults with polycystic ovarian syndrome.

ABSTRACT:

Background

Irisin is a myokine potentially linked to insulin sensitivity. Polycystic ovarian syndrome (PCOS) is a prevalent hormonal condition defined by insulin resistance. Previous studies have reported elevated circulating irisin levels in adult females with PCOS.

Objective

To examine the differences in serum irisin levels between lean and obese adolescents and young adults with PCOS and their respective lean and obese controls and to explore the relationship between irisin levels and the metabolic and reproductive characteristics of the participants.

Design

Cross-sectional study design.

Methods

The study included 60 cases of PCOS and 60 controls. These participants were categorized based on their body mass index (BMI) into lean and obese. Fasting serum iris

SUBMITTER: Majeed S 

PROVIDER: S-EPMC11585921 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature