Hip geometry and strength remain stable the first year after kidney transplantation-an ibandronate/placebo post hoc analysis.

ABSTRACT: The sensitivity of bone mineral density (BMD) to identify patients with high fracture risk after kidney transplantation is low, therefore alternative tools are needed. Hip Structure Analysis (HSA) provides an estimation of hip structural geometry and strength based on conventional DXA scans for hip analyses. We aimed to investigate the effect of antiresorptive therapy on hip geometrical and strength parameters by HSA. In a post hoc analysis of a 12-month randomized, double-blind, placebo-controlled trial evaluating the effect of ibandronate in addition to active vitamin D and calcium in kidney transplant recipients (KTR), we re-analyzed dual total hip and femoral neck DXA scans to measure cortical bone thickness (CBT) in the femoral neck (CBT_NECK), calcar (CBT_CALCAR<

SUBMITTER: Strommen RC 

PROVIDER: S-EPMC11586456 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature