Outcomes of coronary intravascular lithotripsy for the treatment of calcified nodules: a pooled analysis of the Disrupt CAD studies.

ABSTRACT:

Background

Coronary intravascular lithotripsy (IVL) safely facilitates stent implantation in severely calcified lesions.

Aims

This analysis sought to determine the relative impact of IVL on acute and long-term outcomes specifically in calcified nodules (CNs).

Methods

Individual patient-level data (N=155) were pooled from the Disrupt CAD optical coherence tomography (OCT) substudies. Severely calcified lesions with and without CNs were compared by OCT for acute procedural results and for target lesion failure (TLF) at 2 years - a composite of cardiac death, target vessel myocardial infarction, and ischaemia-driven target lesion revascularisation.

Results

A CN was identified in 18.7% (29/155) of lesions. When comparing lesions with and without CNs, there were no

SUBMITTER: Ali ZA 

PROVIDER: S-EPMC11586657 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature