N terminal pro-brain natriuretic peptide level and benefits of chronic total occlusion revascularization.

ABSTRACT:

Background

The management of revascularization of chronic total occlusions (CTOs) remains controversial. Whether specific patients gain survival benefit from CTO revascularization remains unknown.

Objectives

We investigated whether (i) patients with CTO have higher N terminal pro-brain natriuretic peptide (NT pro-BNP) levels than patients without CTO, (ii) in patients with CTO, NT pro-BNP levels predict adverse events, and (iii) those with elevated levels benefit from revascularization.

Methods

In 392 patients with stable, significant coronary artery disease (CAD) and CTO undergoing coronary angiography, rates of all-cause mortality, cardiovascular death, and a composite (cardiovascular death, myocardial infarction and heart failure hospitalizations) were investigated

SUBMITTER: Gold DA 

PROVIDER: S-EPMC11586920 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature