MinD2 modulates cell shape and motility in the archaeon <i>Haloferax volcanii</i>.

ABSTRACT: In bacteria and archaea, proteins of the ParA/MinD family of ATPases regulate the spatiotemporal organization of various cellular cargoes, including cell division proteins, motility structures, chemotaxis systems, and chromosomes. In bacteria, such as Escherichia coli, MinD proteins are crucial for the correct placement of the Z-ring at mid-cell during cell division. However, previous studies have shown that none of the 4 MinD homologs present in the archaeon Haloferax volcanii have a role in cell division, suggesting that these proteins regulate different cellular processes in haloarchaea. Here, we show that while deletion of MinD2 in H. volcanii (∆minD2) does not affect cell growth or division, it impacts cell shape and motility by mispositioning the chemotaxi

SUBMITTER: Patro M 

PROVIDER: S-EPMC11588486 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature