Age Affects Esophageal Secondary Peristalsis More Than Primary as Assessed by FLIP Panometry and High-resolution Manometry.

ABSTRACT: Age-related changes in esophageal function involve increased rates of dysmotility with advancing age (sometimes described as presbyesophagus).^1-4 Specifically, advanced age has been associated with increased lower esophageal sphincter (LES) pressure and decreased peristaltic vigor.^1-4 However, the mechanisms underlying these changes, including the relative relationship of primary peristalsis and secondary peristalsis over the lifespan, remain incompletely understood. Current approaches assess primary peristalsis using high-resolution manometry (HRM), with esophageal motility disorders defined using the Chicago Classification version 4.0 (CCv4.0), and secondary peristalsis using functional lumen imaging probe (FLIP) panometry.^5,6 Although HRM and FLIP panome

SUBMITTER: Arndorfer D 

PROVIDER: S-EPMC11588548 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature