Robotic bronchoscopic needle-based confocal laser endomicroscopy to diagnose peripheral lung nodules.

ABSTRACT:

Background and objective

Robotic bronchoscopy has demonstrated high navigational success in small peripheral lung nodules but the diagnostic yield is discrepantly lower. Needle based confocal laser endomicroscopy (nCLE) enables real-time microscopic imaging at the needle tip. We aim to assess feasibility, safety and needle repositioning based on real-time nCLE-guidance during robotic bronchoscopy in small peripheral lung nodules.

Methods

Patients with suspected peripheral lung cancer underwent fluoroscopy and radial EBUS assisted robotic bronchoscopy. After radial EBUS nodule identification, nCLE-imaging of the target area was performed. nCLE-malignancy and airway/lung parenchyma criteria were used to identify the optimal sampling location. In case airway was visualized, rep

SUBMITTER: Manley CJ 

PROVIDER: S-EPMC11590500 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature