Informed consent and risk communication challenges in antimicrobial clinical trials: a scoping review.

ABSTRACT:

Objectives

Randomised trials for the management of drug-resistant infections are challenging to conduct as target patient populations often lack decision-making capacity, and enrolment windows are typically short. Improving informed consent and risk communication in these trials is especially crucial for protecting patient interests and maximising trial efficiency. This study aimed to understand challenges in risk communication and informed consent in antimicrobial clinical trials.

Design

Scoping review.

Data sources

Searches were conducted in Embase, Medline, CINAHL and Web of Science Core for peer-reviewed English articles that were published from January 2000 to April 2023.

Eligibility criteria

Included articles were empirical studies or expert opinions that

SUBMITTER: Shou Y 

PROVIDER: S-EPMC11590817 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature