Antibiotic Resistance and Presence of Persister Cells in the Biofilm-like Environments in <i>Streptococcus agalactiae</i>.

ABSTRACT: Objectives: This study investigated antibiotic resistance and presence of persister cells in Streptococcus agalactiae strains belonging to capsular types Ia/ST-103, III/ST-17, and V/ST-26 in biofilm-like environments. Results: S. agalactiae strains were susceptible to penicillin, clindamycin, and erythromycin. Resistance genes were associated with tetM (80%), tetO (20%), ermB (80%), and linB (40%). Persister cells were detected in bacterial strains exposed to high concentrations of penicillin, clindamycin, and erythromycin. S. agalactiae capsular type III/ST-17 exhibited the highest percentage of persister cells in response to penicillin and clindamycin, while type Ia/ST-103 presented the lowest percentages of persister cells f

SUBMITTER: Lannes-Costa PS 

PROVIDER: S-EPMC11590950 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature