Methods for Identifying Epilepsy Surgery Targets Using Invasive EEG: A Systematic Review.

ABSTRACT:

Background

The pre-surgical evaluation for drug-resistant epilepsy achieves seizure freedom in only 50-60% of patients. Efforts to identify quantitative intracranial EEG (qEEG) biomarkers of epileptogenicity are needed. This review summarizes and evaluates the design of qEEG studies, discusses barriers to biomarker adoption, and proposes refinements of qEEG study protocols.

Methods

We included exploratory and prediction prognostic studies from MEDLINE and Scopus published between 2017 and 2023 that investigated qEEG markers for identifying the epileptogenic network as the surgical target. Cohort parameters, ground truth references, and analytical approaches were extracted.

Results

Out of 1789 search results, 128 studies were included. The study designs were highly het

SUBMITTER: Ivankovic K 

PROVIDER: S-EPMC11592023 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature