Differential Protein-Coding Gene Expression Profile in Patients with Prostate Cancer.

ABSTRACT:

Background

Prostate cancer is the second most common neoplasm in men, with projections estimating over one million new cases by 2045. Differentially expressed genes can significantly enhance the diagnosis, treatment, monitoring, and prognosis of this disease.

Purpose

to systematically review and analyze validated differentially expressed mRNAs in prostate cancer patients to propose a robust molecular profile for clinical diagnostics.

Methods

A systematic review was conducted following PRISMA guidelines, searching literature databases for mRNAs with validated differential expression in adult prostate cancer patients. Identified mRNAs were analyzed using STRING, Cytoscape, and DrugBank to explore protein-protein interactions and potential drug targets.

Results

A

SUBMITTER: Albarracin-Navas L 

PROVIDER: S-EPMC11592252 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature