Gut Microbiome and Carotid Artery Intima-Media Thickness: A Narrative Review of the Current Scenario.

ABSTRACT: Up to the last update, the gut microbiome (GM) had been associated with a different physiologic host process, including those affecting cardiovascular health. The carotid intima-media thickness (IMT) is an indicator of atherosclerosis and cardiovascular risk. The GM influence on atherosclerosis progression has garnered growing attention in recent years but the consensus in subclinical atherosclerosis remains elusive. The aim of this narrative review is to investigate the connection between the GM and carotid IMT, encompassing mechanisms like the microbiome impact on metabolite production, and systemic inflammation, and its effects on endothelial function. The literature analysis revealed that the GM appears to exert an influence on carotid IMT development, likely through mechanisms involvi

SUBMITTER: Pala B 

PROVIDER: S-EPMC11592993 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature