Multi-Centre Study of Progression Factors and Intravesical Recurrence in Patients with Urothelial Carcinoma of the Upper Urinary Tract.

ABSTRACT:

Background/objectives

A retrospective analysis was conducted to identify factors associated with disease progression and intravesical recurrence (IVR) in a multi-centre cohort of patients with upper urinary tract urothelial carcinoma (UTUC) treated surgically between 2015 and 2021.

Methods

Progression-free survival (PFS) and IVR-free survival were evaluated using a Kaplan-Meier survival curve and a Log-Rank test. Prognostic factors for progression and IVR were analysed using Cox logistic regression analysis.

Results

A total of 170 patients were analysed. Up to 32.9% developed progression within 65.64 ± 3.44 months. Multivariate analysis showed that pT (HR 2.9, 95%CI 1.54-5.48, p = 0.01), margin status (HR 2.89, 95%CI 2.88-57.68, p = 0.01), and lymphovasc

SUBMITTER: Garcia-Morales L 

PROVIDER: S-EPMC11593072 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature