First Detection of West Nile Virus by Nasopharyngeal Swab, Followed by Phylogenetic Analysis.

ABSTRACT: West Nile Virus, an arthropod-borne RNA virus, may result in severe neurological disease. West Nile neuroinvasive disease is characterized by meningitis, encephalitis, and possible acute flaccid paralysis. Here, we report a case of neuroinvasive WNV in a 65-year-old woman hospitalized for hyperpyrexia, chills, intense asthenia, and continuous vomiting. Within days, her clinical condition worsened with the onset of severe neurological symptoms, leading to her death within 10 days despite supportive therapies being administered. The diagnosis of West Nile disease was made through nucleic acid amplification testing (NAAT) on blood and cerebrospinal fluid. However, in the final stages of the illness, cerebrospinal fluid collection was not possible due to the patient's critical condition, and a

SUBMITTER: Zuddas C 

PROVIDER: S-EPMC11597865 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature