Genomic Sequence of the Threespine Stickleback Iridovirus (TSIV) from Wild <i>Gasterosteus aculeatus</i> in Stormy Lake, Alaska.

ABSTRACT: The threespine stickleback iridovirus (TSIV), a double-stranded DNA virus, was the first megalocytivirus detected in wild North American fishes. We report a second occurrence of TSIV in threespine stickleback (Gasterosteus aculeatus) from Stormy Lake, Alaska, and assemble a nearly complete genome of TSIV. The 115-kilobase TSIV genome contains 94 open reading frames (ORFs), with 91 that share homology with other known iridoviruses. We identify three ORFs that likely originate from recent lateral gene transfers from a eukaryotic host and one ORF with homology to B22 poxvirus proteins that likely originated from a lateral gene transfer between viruses. Phylogenetic analysis of 24 iridovirus core genes and pairwise sequence identity analysis support TSIV as a divergent sister taxon to o

SUBMITTER: Yoxsimer AM 

PROVIDER: S-EPMC11598847 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature