PaCO₂ Association with Outcomes of Patients with Traumatic Brain Injury at High Altitude: A Prospective Single-Center Cohort Study.

ABSTRACT:

Background

Partial pressure of carbon dioxide (PaCO₂) is generally known to influence outcome in patients with traumatic brain injury (TBI) at normal altitudes. Less is known about specific relationships of PaCO₂ levels and clinical outcomes at high altitudes.

Methods

This is a prospective single-center cohort of consecutive patients with TBI admitted to a trauma center located at 2600 m above sea level. An unfavorable outcome was defined as a Glasgow Outcome Scale-Extended (GOSE) score < 4 at the 6-month follow-up.

Results

We had a total of 81 patients with complete data, 80% (65/81) were men, and the median (interquartile range) age was 36 (25-50) years. Median Glasgow Coma Scale (GCS) score on admission was 9 (6-14); 49% (40/81) of patients ha

SUBMITTER: Caceres E 

PROVIDER: S-EPMC11599390 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature