Impact of a two step antimicrobial stewardship program in a paediatric haematology and oncology unit.

ABSTRACT:

Objective

To describe the implementation of a multi-step antimicrobial stewardship program in a haemato-oncology and stem cell transplantation program unit. Methods: Pre-post quasi-experimental study with two interrupted time-series analyses, conducted between 01/01/2019 and 31/12/2022 in the Paediatric Haemato-Oncology Unit of the Padua Paediatric Hospital. The interventions were: (1) 02/2020: dissemination of febrile neutropenia clinical pathways, (2) April 2021: provision of the clinical pathways via a customized App (Firstline.org) and implementation of a twice-a-week prospective audit and feedback. The main outcome was antibiotic consumption measured by days of administered therapy (DOTs)/1000 patients' days for all antibiotics and most used molecules.

Results

The first

SUBMITTER: Liberati C 

PROVIDER: S-EPMC11599578 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature