Changes in the intestinal microbiota of Japanese children during the first 3.5 years of life.

ABSTRACT: Human gut microbiota plays a crucial role in health and disease. Infancy is a critical period for gut microbiota maturation and immune system development and has the potential to affect long-term health. Understanding the development of gut microbiota in Japanese children is essential because of regional differences and the long-term health effects of the early gut microbiota. However, while several longitudinal studies in Japan have explored the development of the gut microbiota after birth, more extended follow-up periods are still needed. In this study, we aimed to analyze the gut microbiota of 106 Japanese mother-child pairs from the Chiba Study of Mother and Child Health, Japan, over 3.5 years. The results showed that the alpha diversity of the gut microbiota in children increased wit

SUBMITTER: Tsuruoka Y 

PROVIDER: S-EPMC11599607 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature