A multicenter study to evaluate the analytical precision by pathologists using the Aperio GT 450 DX.

ABSTRACT:

Background

Digital pathology systems (DPS) are emerging as capable technologies for clinical practice. Studies have analyzed pathologists' diagnostic concordance by comparing reviews of whole slide images (WSIs) to glass slides (e.g., accuracy). This observational study evaluated the reproducibility of pathologists' diagnostic reviews using the Aperio GT 450 DX under slightly different conditions (precision).

Method

Diagnostic precision was tested in three conditions: intra-system (within systems), inter-system/site (between systems/sites), and intra- and inter-pathologist (within and between pathologists). A total of five study/reading pathologists (one pathologist each for intra-system, inter-system/site, and three for intra-pathologist/inter-pathologist analyses) were ass

SUBMITTER: Bauer TW 

PROVIDER: S-EPMC11600015 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature