Impact of SARS-CoV-2 variants on COVID-19 symptomatology and severity during five waves.

ABSTRACT:

Background

SARS-CoV-2 variants have distinct features of transmissibility, infectivity, and aggressiveness that may cause different clinical manifestations. A better understanding of the disease presentation and progression could help to outline more precise preventive and treatment frameworks. This study describes the differences in COVID-19 presentation and outcomes across five variant waves.

Methods

This prospective cohort was conducted in Serrana, São Paulo State, Brazil. Clinical and demographic data was obtained from June 2020 to December 2022 as part of an enhanced health surveillance system for COVID-19, based on increasing access to diagnostic testing for SARS-CoV-2 and patient follow-up. Individuals were assessed for COVID-19 symptoms and comorbidities. Mild cases

SUBMITTER: Gomes BBM 

PROVIDER: S-EPMC11600076 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature