Food Consumption and Risk of Islet Autoimmunity and Type 1 Diabetes in Children at Increased Genetic Susceptibility for Type 1 Diabetes.

ABSTRACT:

Background

Prospective longitudinal evidence considering the entire childhood food consumption in relation to the development of islet autoimmunity (IA or) type 1 diabetes is lacking.

Objectives

We studied the associations of consumption of various foods and their combinations with IA and type 1 diabetes risk.

Methods

Children with genetic susceptibility to type 1 diabetes born in 1996-2004 were followed from birth up to ≤6 y of age in the prospective birth cohort type 1 diabetes prediction and prevention study (n = 5674). Exposure variables included 34 food groups covering the entire diet based on repeated 3-d food records at ages 3 mo to 6 y. Endpoints were islet cell antibodies plus biochemical IA (n = 247), multiple biochemical IA (n = 206), and type 1 diabetes (n

SUBMITTER: Virtanen SM 

PROVIDER: S-EPMC11600112 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature